BixBench current item

bix-52-q2

Question

What is the mean of per-chromosome densities (CpGs per base pair) for filtered (>90% or <10% methylation) unique age-related CpGs across all chromosomes (only including those with at least one filtered CpG) in the Jackdaw genome?

Accepted answer
(1.03E-07,1.23E-07)
Domain
general

Comparison

Pass counts and token totals across the same three replicates.

AgentGalaxy-API codeOpen-ended code
Codex GPT-5.53/3
replicate 1 replicate 2 replicate 3
1.85M total
3/3
replicate 1 replicate 2 replicate 3
304.2K total
Codex GPT-5.6 Sol3/3
replicate 1 replicate 2 replicate 3
9.14M total
3/3
replicate 1 replicate 2 replicate 3
334.5K total
Codex GPT-5.6 Luna2/3
replicate 1 replicate 2 replicate 3
30.33M total
3/3
replicate 1 replicate 2 replicate 3
601.2K total
DeepSeek V4 Pro via Codex3/3
replicate 1 replicate 2 replicate 3
9.49M total
3/3
replicate 1 replicate 2 replicate 3
4.52M total
DeepSeek V4 Pro via Claude Codesuperseded3/3
replicate 1 replicate 2 replicate 3
12.89M total
3/3
replicate 1 replicate 2 replicate 3
872.9K total

Execution condition

Galaxy-API code with skills

Codex GPT-5.5

3 primary replicates
Codex GPT-5.5

replicate 1

passUDT-only
Answer1.1282568023118122e-07
Workflow
Galaxy UDTCpG filtering and densitymethylation filtering
Total tokens
610.3K
Output
8.3K
Codex GPT-5.5

replicate 2

passUDT-only
Answer1.12825680231e-07
Workflow
Galaxy UDTCpG filtering and densitymethylation filtering
Total tokens
817.5K
Output
8.3K
Codex GPT-5.5

replicate 3

passUDT-only
Answer1.1282568023118122e-07
Workflow
Galaxy UDTCpG filtering and densitymethylation filtering
Total tokens
417.4K
Output
5.5K

Codex GPT-5.6 Sol

3 primary replicates
Codex GPT-5.6 Sol

replicate 1

pass
Answer1.12826e-07
Workflow
Csv To TabularFilter TabularSelect columnsmore stepsSummary statisticsCpG filtering and density
Total tokens
3.09M
Output
10.6K
Codex GPT-5.6 Sol

replicate 2

pass
Answer1.1282568023118e-07
Workflow
Csv To TabularFilter rowsDatamash summarymore stepsAdd derived columnCpG filtering and density
Total tokens
3.42M
Output
12.8K
Codex GPT-5.6 Sol

replicate 3

pass
Answer1.1282568023118e-07
Workflow
Csv To TabularFilter rowsDatamash summarymore stepsAdd derived columnCpG filtering and density
Total tokens
2.64M
Output
10.5K

Codex GPT-5.6 Luna

3 primary replicates
Codex GPT-5.6 Luna

replicate 1

pass
Answer1.1282568023118121808590038207938999097997615882758e-7
Workflow
Csv To TabularFilter rowsDatamash summarymore stepsAdd derived columnCpG filtering and density
Total tokens
9.72M
Output
30.8K
Codex GPT-5.6 Luna

replicate 2

pass
Answer1.1282568023118e-07
Workflow
Csv To TabularFilter rowsSelect columnsmore stepsTp Sort Header ToolCpG filtering and density
Total tokens
15.44M
Output
41.5K
Codex GPT-5.6 Luna

replicate 3

fail

Why it missed

Filtering pipeline dropped qualifying chromosomesThis Galaxy branch retained filtered loci on only 18 chromosomes, while the verified strict-cutoff calculation has 51 unique CpGs across 20 chromosomes. Averaging the incomplete table produced 9.507e-08 instead of about 1.128e-07.
Answer9.5074614121924e-08
Workflow
Csv To TabularFilter TabularTp Grep Toolmore stepsTable ComputeCpG filtering and density
Total tokens
5.17M
Output
28.3K

DeepSeek V4 Pro via Codex

3 primary replicates
DeepSeek V4 Pro via Codex

replicate 1

pass
Answer1.1282568023118e-07
Workflow
Csv To TabularFilter rowsFilter Tabularmore stepsCpG filtering and densitymethylation filtering
Total tokens
2.23M
Output
20.4K
DeepSeek V4 Pro via Codex

replicate 2

pass
Answer1.1282568023118119e-07
Workflow
Filter rowsGroup and aggregateRemove headermore stepsCpG filtering and densitymethylation filtering
Total tokens
3.91M
Output
24.8K
DeepSeek V4 Pro via Codex

replicate 3

pass
Answer1.1282568023118119e-07
Workflow
Filter rowsGroup and aggregateSort rowsmore stepsmethylation filteringmean summary
Total tokens
3.35M
Output
28.3K

DeepSeek V4 Pro via Claude CodeSuperseded

3 primary replicates
DeepSeek V4 Pro via Claude Code

replicate 1

passUDT + standard tools
Answer1.128256802311812e-07
Workflow
Tp Head ToolGalaxy UDTGroup and aggregateCpG filtering and densitymethylation filtering
Total tokens
3.67M
Output
32.2K
DeepSeek V4 Pro via Claude Code

replicate 2

passUDT + standard tools
Answer1.1282568023e-07
Workflow
Filter TabularGalaxy UDTCpG filtering and densitymethylation filtering
Total tokens
6.70M
Output
60.1K
DeepSeek V4 Pro via Claude Code

replicate 3

pass
Answer1.12826e-07
Workflow
Filter rowsGroup and aggregateFilter Tabularmore stepsSummary statisticsCpG filtering and density
Total tokens
2.52M
Output
22.3K

Execution condition

Open-ended code with skills

Codex GPT-5.5

3 primary replicates
Codex GPT-5.5

replicate 1

pass
Answer1.1282568023118122e-07
Workflow
Local analysisCpG filtering and densitymethylation filtering
Total tokens
83.0K
Output
2.7K
Codex GPT-5.5

replicate 2

pass
Answer1.1282568023118122e-07
Workflow
Local analysisCpG filtering and densitymethylation filtering
Total tokens
90.7K
Output
2.3K
Codex GPT-5.5

replicate 3

pass
Answer0.00000011282568023118121808590038207938999097997615882758
Workflow
Local analysisCpG filtering and densitymethylation filtering
Total tokens
130.5K
Output
3.1K

Codex GPT-5.6 Sol

3 primary replicates
Codex GPT-5.6 Sol

replicate 1

pass
Answer1.128256802311812e-7
Workflow
Local analysis
Total tokens
98.1K
Output
2.2K
Codex GPT-5.6 Sol

replicate 2

pass
Answer1.1282568023118122e-07
Workflow
Local analysis
Total tokens
140.1K
Output
3.3K
Codex GPT-5.6 Sol

replicate 3

pass
Answer1.1282568023118121808590038207938999098e-7
Workflow
Local analysis
Total tokens
96.4K
Output
2.6K

Codex GPT-5.6 Luna

3 primary replicates
Codex GPT-5.6 Luna

replicate 1

pass
Answer1.12825680231181218085900382079389990979976158827575984694831e-07
Workflow
Local analysis
Total tokens
275.6K
Output
7.7K
Codex GPT-5.6 Luna

replicate 2

pass
Answer1.1282568023118121808590038207938999097997615882758e-7
Workflow
Local analysis
Total tokens
149.2K
Output
4.4K
Codex GPT-5.6 Luna

replicate 3

pass
Answer1.1282568023118121808590038207938999e-7
Workflow
Local analysis
Total tokens
176.4K
Output
6.3K

DeepSeek V4 Pro via Codex

3 primary replicates
DeepSeek V4 Pro via Codex

replicate 1

pass
Answer1.1282568023118122e-07
Workflow
Local analysisCpG filtering and densitymethylation filtering
Total tokens
640.5K
Output
10.9K
DeepSeek V4 Pro via Codex

replicate 2

pass
Answer1.1282568023118122e-07
Workflow
Local analysisCpG filtering and densitymethylation filteringmean summarymedian summary
Total tokens
2.16M
Output
24.5K
DeepSeek V4 Pro via Codex

replicate 3

pass
Answer1.1282568023118122e-07
Workflow
Local analysisCpG filtering and densitymethylation filteringmean summarymedian summary
Total tokens
1.73M
Output
23.3K

DeepSeek V4 Pro via Claude CodeSuperseded

3 primary replicates
DeepSeek V4 Pro via Claude Code

replicate 1

pass
Answer1.1282568023118119e-07
Workflow
Local analysisCpG filtering and densitymethylation filtering
Total tokens
213.8K
Output
3.9K
DeepSeek V4 Pro via Claude Code

replicate 2

pass
Answer1.128256802311812e-07
Workflow
Local analysisCpG filtering and densitymethylation filtering
Total tokens
423.0K
Output
7.1K
DeepSeek V4 Pro via Claude Code

replicate 3

pass
Answer1.128256802311812e-07
Workflow
Local analysisCpG filtering and densitymethylation filtering
Total tokens
236.2K
Output
4.0K

bix-52-q2 · October 2026 · three additional replicates

GPT-5.6 Sol · token optimization

Galaxy-API code, high reasoning, Fast service. Previous runs are retained above.

Open-ended code averaged 0.11M tokens; previous website Galaxy averaged 3.05M; the new Galaxy runs averaged 1.72M, or 15.41× Open-ended code. Each mean covers three replicates of this same task with GPT-5.6 Sol.

Cached input is already included in input tokens. Full nested tool/job evidence is in each HF run's galaxy_execution_records.tar.gz, with an accompanying member index.

Optimization overview and all 150 runs