bix-37-q4 | Current BixBench results

New token-optimization experiment

Three additional GPT-5.6 Sol Galaxy replicates are available separately. Previous results remain unchanged.

View the October 2026 batch and its run records

Question

What is the log2 fold change value (rounded to 2 decimal places) for ENO1 when comparing tumor samples to normal samples in the proteomics dataset?

Accepted answer: 2.27
Domain: general

Comparison

Pass counts and token totals across the same three replicates.

Agent	Galaxy-API code	Open-ended code
Codex GPT-5.5	3/3 replicate 1 replicate 2 replicate 3 2.39M total	3/3 replicate 1 replicate 2 replicate 3 369.4K total
Codex GPT-5.6 Sol	3/3 replicate 1 replicate 2 replicate 3 3.80M total	3/3 replicate 1 replicate 2 replicate 3 269.8K total
Codex GPT-5.6 Luna	3/3 replicate 1 replicate 2 replicate 3 5.67M total	3/3 replicate 1 replicate 2 replicate 3 324.8K total
DeepSeek V4 Pro via Codex	3/3 replicate 1 replicate 2 replicate 3 3.18M total	3/3 replicate 1 replicate 2 replicate 3 278.3K total
DeepSeek V4 Pro via Claude Codesuperseded	3/3 replicate 1 replicate 2 replicate 3 2.02M total	3/3 replicate 1 replicate 2 replicate 3 614.9K total

Execution condition

Galaxy-API code with skills

Codex GPT-5.5

3 primary replicates

Codex GPT-5.5

replicate 1

pass

Answer2.27

Workflow

Excel to tabularfold-change calculation

Total tokens: 657.1K
Output: 4.2K

Galaxy history Run trace

Codex GPT-5.5

replicate 2

pass

Answer2.27

Workflow

Excel to tabularFilter Tabularfold-change calculation

Total tokens: 871.3K
Output: 6.3K

Galaxy history Run trace

Codex GPT-5.5

replicate 3

pass

Answer2.27

Workflow

Excel to tabularMatch rowsSelect columnsfold-change calculation

Total tokens: 865.7K
Output: 5.3K

Galaxy history Run trace

Codex GPT-5.6 Sol

3 primary replicates

Codex GPT-5.6 Sol

replicate 1

pass

Answer2.27

Workflow

Excel to tabularAdd derived columnfold-change calculation

Total tokens: 1.28M
Output: 7.3K

Galaxy history Run trace

Codex GPT-5.6 Sol

replicate 2

pass

Answer2.27

Workflow

Excel to tabularAdd derived columnfold-change calculation

Total tokens: 1.01M
Output: 6.9K

Galaxy history Run trace

Codex GPT-5.6 Sol

replicate 3

pass

Answer2.27

Workflow

Excel to tabularAdd derived columnfold-change calculation

Total tokens: 1.51M
Output: 7.4K

Galaxy history Run trace

Codex GPT-5.6 Luna

3 primary replicates

Codex GPT-5.6 Luna

replicate 1

pass

Answer2.27

Workflow

Excel to tabularFilter Tabularfold-change calculation

Total tokens: 1.65M
Output: 12.1K

Galaxy history Run trace

Codex GPT-5.6 Luna

replicate 2

pass

Answer2.27

Workflow

Excel to tabularFilter Tabularfold-change calculation

Total tokens: 1.98M
Output: 14.8K

Galaxy history Run trace

Codex GPT-5.6 Luna

replicate 3

pass

Answer2.27

Workflow

Excel to tabularAdd derived columnfold-change calculation

Total tokens: 2.04M
Output: 20.4K

Galaxy history Run trace

DeepSeek V4 Pro via Codex

3 primary replicates

DeepSeek V4 Pro via Codex

replicate 1

pass

Answer2.27

Workflow

Excel to tabularFilter rowsfold-change calculation

Total tokens: 556.8K
Output: 8.1K

Galaxy history Run trace

DeepSeek V4 Pro via Codex

replicate 2

pass

Answer2.27

Workflow

Excel to tabularFilter TabularFilter rowsfold-change calculation

Total tokens: 1.41M
Output: 12.2K

Galaxy history Run trace

DeepSeek V4 Pro via Codex

replicate 3

pass

Answer2.27

Workflow

Excel to tabularFilter Tabular

Total tokens: 1.21M
Output: 12.8K

Galaxy history Run trace

DeepSeek V4 Pro via Claude CodeSuperseded

3 primary replicates

DeepSeek V4 Pro via Claude Code

replicate 1

pass

Answer2.27

Workflow

Galaxy via BioBlendfold-change calculation

Total tokens: 517.6K
Output: 7.2K

Galaxy history Run trace

DeepSeek V4 Pro via Claude Code

replicate 2

pass

Answer2.27

Workflow

Excel to tabularfold-change calculation

Total tokens: 606.1K
Output: 5.7K

Galaxy history Run trace

DeepSeek V4 Pro via Claude Code

replicate 3

pass

Answer2.27

Workflow

Excel to tabularFilter Tabularfold-change calculation

Total tokens: 898.3K
Output: 9.9K

Galaxy history Run trace

Execution condition

Open-ended code with skills

Codex GPT-5.5

3 primary replicates

Codex GPT-5.5

replicate 1

pass

Answer2.27

Workflow

Local analysisfold-change calculation

Total tokens: 105.3K
Output: 1.7K

Run trace

Codex GPT-5.5

replicate 2

pass

Answer2.27

Workflow

Local analysis

Total tokens: 144.7K
Output: 1.7K

Run trace

Codex GPT-5.5

replicate 3

pass

Answer2.27

Workflow

Local analysisfold-change calculation

Total tokens: 119.3K
Output: 1.6K

Run trace

Codex GPT-5.6 Sol

3 primary replicates

Codex GPT-5.6 Sol

replicate 1

pass

Answer2.27

Workflow

Local analysis

Total tokens: 97.1K
Output: 1.1K

Run trace

Codex GPT-5.6 Sol

replicate 2

pass

Answer2.27

Workflow

Local analysis

Total tokens: 111.2K
Output: 1.1K

Run trace

Codex GPT-5.6 Sol

replicate 3

pass

Answer2.27

Workflow

Local analysis

Total tokens: 61.5K
Output: 1.1K

Run trace

Codex GPT-5.6 Luna

3 primary replicates

Codex GPT-5.6 Luna

replicate 1

pass

Answer2.27

Workflow

Local analysis

Total tokens: 120.5K
Output: 1.7K

Run trace

Codex GPT-5.6 Luna

replicate 2

pass

Answer2.27

Workflow

Local analysis

Total tokens: 85.3K
Output: 1.9K

Run trace

Codex GPT-5.6 Luna

replicate 3

pass

Answer2.27

Workflow

Local analysis

Total tokens: 119.1K
Output: 1.6K

Run trace

DeepSeek V4 Pro via Codex

3 primary replicates

DeepSeek V4 Pro via Codex

replicate 1

pass

Answer2.27

Workflow

Local analysis

Total tokens: 132.6K
Output: 2.2K

Run trace

DeepSeek V4 Pro via Codex

replicate 2

pass

Answer2.27

Workflow

Local analysis

Total tokens: 63.8K
Output: 1.5K

Run trace

DeepSeek V4 Pro via Codex

replicate 3

pass

Answer2.27

Workflow

Local analysisfold-change calculation

Total tokens: 81.9K
Output: 2.1K

Run trace

DeepSeek V4 Pro via Claude CodeSuperseded

3 primary replicates

DeepSeek V4 Pro via Claude Code

replicate 1

pass

Answer2.27

Workflow

Local analysisfold-change calculation

Total tokens: 224.2K
Output: 2.6K

Run trace

DeepSeek V4 Pro via Claude Code

replicate 2

pass

Answer2.27

Workflow

Local analysisfold-change calculation

Total tokens: 118.0K
Output: 1.2K

Run trace

DeepSeek V4 Pro via Claude Code

replicate 3

pass

Answer2.27

Workflow

Local analysisfold-change calculation

Total tokens: 272.7K
Output: 2.8K

Run trace

bix-37-q4 · October 2026 · three additional replicates

GPT-5.6 Sol · token optimization

Galaxy-API code, high reasoning, Fast service. Previous runs are retained above.

Galaxy-API code · October 2026

replicate 1

Correct

Answer2.27

Total tokens: 443.7K
Input: 439.5K
Cached input: 419.3K
Output: 4.2K

Run trace Final answer Galaxy history

Galaxy-API code · October 2026

replicate 2

Correct

Answer2.27

Total tokens: 557.5K
Input: 547.6K
Cached input: 506.2K
Output: 9.9K

Run trace Final answer Galaxy history

Galaxy-API code · October 2026

replicate 3

Correct

Answer2.27

Total tokens: 945.1K
Input: 940.7K
Cached input: 891.5K
Output: 4.4K

Run trace Final answer Galaxy history

Open-ended code averaged 0.09M tokens; previous website Galaxy averaged 1.27M; the new Galaxy runs averaged 0.65M, or 7.21× Open-ended code. Each mean covers three replicates of this same task with GPT-5.6 Sol.

Cached input is already included in input tokens. Full nested tool/job evidence is in each HF run's galaxy_execution_records.tar.gz, with an accompanying member index.

Optimization overview and all 150 runs