BixBench current item

bix-12-q4

Question

What is the Mann-Whitney U statistic when comparing parsimony informative site percentages between animals and fungi?

Accepted answer
6948.0
Domain
phylogenetics

Comparison

Pass counts and token totals across the same three replicates.

AgentGalaxy-API codeOpen-ended code
Codex GPT-5.53/3
replicate 1 replicate 2 replicate 3
3.59M total
3/3
replicate 1 replicate 2 replicate 3
1.29M total
Codex GPT-5.6 Sol3/3
replicate 1 replicate 2 replicate 3
21.00M total
3/3
replicate 1 replicate 2 replicate 3
1.82M total
Codex GPT-5.6 Luna3/3
replicate 1 replicate 2 replicate 3
27.49M total
2/3
replicate 1 replicate 2 replicate 3
4.16M total
DeepSeek V4 Pro via Codex3/3
replicate 1 replicate 2 replicate 3
12.51M total
3/3
replicate 1 replicate 2 replicate 3
3.04M total
DeepSeek V4 Pro via Claude Codesuperseded1/3
replicate 1 replicate 2 replicate 3
9.17M total
0/3
replicate 1 replicate 2 replicate 3
3.67M total

Execution condition

Galaxy-API code with skills

Codex GPT-5.5

3 primary replicates
Codex GPT-5.5

replicate 1

passUDT-only
Answer6948
Workflow
Galaxy UDTMAFFTSciPyMann-Whitney U
Total tokens
928.7K
Output
8.4K
Codex GPT-5.5

replicate 2

passUDT-only
Answer6948
Workflow
Galaxy UDTPhyKITSciPyMAFFT
Total tokens
1.21M
Output
11.9K
Codex GPT-5.5

replicate 3

passUDT + standard tools
Answer6948
Workflow
Galaxy UDTNonparametric Rank TestsPhyKITmore stepsscikit-learnMAFFT
Total tokens
1.45M
Output
14.9K

Codex GPT-5.6 Sol

3 primary replicates
Codex GPT-5.6 Sol

replicate 1

passUDT + standard tools
Answer6948
Workflow
Galaxy UDTNonparametric Rank TestsPhyKITMAFFT
Total tokens
1.26M
Output
12.2K
Codex GPT-5.6 Sol

replicate 2

pass
Answer6948
Workflow
UnzipPhykit Alignment BasedCollapse DatasetNonparametric Rank Tests
Total tokens
17.10M
Output
28.9K
Codex GPT-5.6 Sol

replicate 3

passUDT + standard tools
Answer6948
Workflow
Galaxy UDTNonparametric Rank TestsMAFFTPhyKIT
Total tokens
2.64M
Output
12.7K

Codex GPT-5.6 Luna

3 primary replicates
Codex GPT-5.6 Luna

replicate 1

passUDT + standard tools
Answer6948
Workflow
UnzipPhykit Alignment BasedGalaxy UDTmore stepsSciPyMann-Whitney U
Total tokens
14.33M
Output
38.9K
Codex GPT-5.6 Luna

replicate 2

passUDT + standard tools
Answer6948
Workflow
UnzipPhykit Alignment BasedGalaxy UDTNonparametric Rank TestsSciPyMAFFT
Total tokens
4.70M
Output
23.2K
Codex GPT-5.6 Luna

replicate 3

passUDT + standard tools
Answer6948
Workflow
UnzipPhykit Alignment BasedGalaxy UDTNonparametric Rank TestsMAFFTBUSCO
Total tokens
8.45M
Output
33.2K

DeepSeek V4 Pro via Codex

3 primary replicates
DeepSeek V4 Pro via Codex

replicate 1

passUDT + standard tools
Answer6948
Workflow
Galaxy UDTNonparametric Rank TestsMAFFTPhyKIT
Total tokens
3.00M
Output
28.6K
DeepSeek V4 Pro via Codex

replicate 2

passUDT + standard tools
Answer6948
Workflow
Galaxy UDTNonparametric Rank TestsMAFFTPhyKIT
Total tokens
5.56M
Output
24.8K
DeepSeek V4 Pro via Codex

replicate 3

passUDT + standard tools
Answer6948
Workflow
Galaxy UDTNonparametric Rank TestsPhyKITMAFFT
Total tokens
3.95M
Output
23.0K

DeepSeek V4 Pro via Claude CodeSuperseded

3 primary replicates
DeepSeek V4 Pro via Claude Code

replicate 1

failUDT + standard tools

Why it missed

Scientific implementation mismatchThis custom UDT produced a parsimony-informative-site distribution that differed from the gap-aware implementation, yielding U=6160 instead of 6948.
Answer6160
Workflow
Phykit Alignment BasedGalaxy UDTNonparametric Rank TestsMAFFT
Total tokens
4.16M
Output
34.5K
DeepSeek V4 Pro via Claude Code

replicate 2

failUDT + standard tools

Why it missed

Scientific implementation mismatchThis custom UDT produced a different parsimony-informative-site distribution before the test, yielding U=7048.5 instead of 6948.
Answer7048.5
Workflow
Galaxy UDTNonparametric Rank TestsBiopythonPhyKITMAFFT
Total tokens
2.03M
Output
21.7K
DeepSeek V4 Pro via Claude Code

replicate 3

passUDT + standard tools
Answer6948
Workflow
UnzipPhykit Alignment BasedGalaxy UDTmore stepsBiopythonMAFFT
Total tokens
2.98M
Output
35.7K

Execution condition

Open-ended code with skills

Codex GPT-5.5

3 primary replicates
Codex GPT-5.5

replicate 1

pass
Answer6948
Workflow
Local analysisMAFFTSciPymean summarymedian summary
Total tokens
359.2K
Output
9.5K
Codex GPT-5.5

replicate 2

pass
Answer6948.0
Workflow
Local analysisBUSCOMAFFTSciPyBiopythonMann-Whitney U
Total tokens
338.3K
Output
7.2K
Codex GPT-5.5

replicate 3

pass
Answer6948.0
Workflow
Local analysisBUSCOMAFFTSciPyBiopython
Total tokens
596.1K
Output
8.2K

Codex GPT-5.6 Sol

3 primary replicates
Codex GPT-5.6 Sol

replicate 1

pass
Answer6948
Workflow
Local analysis
Total tokens
713.8K
Output
8.1K
Codex GPT-5.6 Sol

replicate 2

pass
Answer6948
Workflow
Local analysis
Total tokens
579.5K
Output
7.8K
Codex GPT-5.6 Sol

replicate 3

pass
Answer6948
Workflow
Local analysis
Total tokens
528.6K
Output
7.2K

Codex GPT-5.6 Luna

3 primary replicates
Codex GPT-5.6 Luna

replicate 1

fail

Why it missed

Alignment population was restrictedThis run required every alignment to contain all four taxa, reducing the test to 22 animal and 211 fungal observations and producing U=1162. The benchmark comparison uses all 241 animal and 255 fungal alignments and gives U=6948.
Answer1162.0
Workflow
Local analysis
Total tokens
1.67M
Output
32.3K
Codex GPT-5.6 Luna

replicate 2

pass
Answer6948
Workflow
Local analysis
Total tokens
1.25M
Output
24.1K
Codex GPT-5.6 Luna

replicate 3

pass
Answer6948
Workflow
Local analysis
Total tokens
1.24M
Output
25.7K

DeepSeek V4 Pro via Codex

3 primary replicates
DeepSeek V4 Pro via Codex

replicate 1

pass
Answer6948.0
Workflow
Local analysisBUSCOMAFFTBiopythonSciPyPhyKIT
Total tokens
789.3K
Output
5.3K
DeepSeek V4 Pro via Codex

replicate 2

pass
Answer6948.0
Workflow
Local analysisBUSCOMAFFTSciPy
Total tokens
822.9K
Output
6.5K
DeepSeek V4 Pro via Codex

replicate 3

pass
Answer6948
Workflow
Local analysisBUSCOMAFFTSciPyMann-Whitney UPhyKIT
Total tokens
1.42M
Output
19.7K

DeepSeek V4 Pro via Claude CodeSuperseded

3 primary replicates
DeepSeek V4 Pro via Claude Code

replicate 1

fail

Why it missed

Data scope changedThis run restricted both groups to the 241 orthogroups shared by the two archives instead of comparing all 241 animal and 255 fungal alignments. That changed the tested distributions and produced U=6350.
Answer6350
Workflow
Local analysisBUSCOMAFFTSciPyMann-Whitney U
Total tokens
2.02M
Output
27.7K
DeepSeek V4 Pro via Claude Code

replicate 2

fail

Why it missed

Data scope and character handlingThis run restricted both groups to 241 shared orthogroups and also counted gaps as a character state. Those choices changed the distributions and produced U=5604.
Answer5604
Workflow
Local analysisBUSCOMAFFTSciPyMann-Whitney U
Total tokens
1.03M
Output
16.6K
DeepSeek V4 Pro via Claude Code

replicate 3

fail

Why it missed

Data scope changedThis run restricted both groups to the 241 orthogroups shared by the two archives instead of comparing all 241 animal and 255 fungal alignments. That changed the tested distributions and produced U=6350.
Answer6350
Workflow
Local analysisMAFFTSciPyMann-Whitney Umean summarymedian summary
Total tokens
617.1K
Output
17.2K

bix-12-q4 · October 2026 · three additional replicates

GPT-5.6 Sol · token optimization

Galaxy-API code, high reasoning, Fast service. Previous runs are retained above.

Open-ended code averaged 0.61M tokens; previous website Galaxy averaged 7.00M; the new Galaxy runs averaged 3.23M, or 5.32× Open-ended code. Each mean covers three replicates of this same task with GPT-5.6 Sol.

Cached input is already included in input tokens. Full nested tool/job evidence is in each HF run's galaxy_execution_records.tar.gz, with an accompanying member index.

Optimization overview and all 150 runs