perturb-seq-effect-q1

Question

You are given the cellranger output of a CRISPR perturb-seq experiment in perturb.seq.effect.q1.tar.gz where cell features are at filtered_feature_bc_matrix/features.tsv.gz, counts are at filtered_feature_bc_matrix/matrix.mtx.gz, barcodes are at filtered_feature_bc_matrix/barcodes.tsv.gz, guide assignment per cell is at perturb_protospacer_calls_per_cell.csv, and guide reference at feature_reference.csv. I am interested in finding guides which robustly knockdown the interferon gamma pathway. We need to decide which target gene from this screen to explore in a follow up screen - which gene target should be selected? Respond with a single gene target name (i.e. CCL6).

Inferred answer

ISG15Uniquely inferred from submitted scores.

Domain

Single-cell

Question style

Synthetic/Augmented Data

An answer can be uniquely inferred for 54 of 100 questions from submitted scores. Green: correct · Red: incorrect. For questions without a uniquely determined answer: Blue: matches prediction · Orange: differs from prediction. These are inferred answer checks, not official per-question grades.