Question
Using the Ensembl VEP API, determine the consequence for the following variant rs2136714166. Respond with a single word.
- Predicted answer
upstream_gene_variantMost likely answer for this question; not uniquely determined from submitted scores.
- Domain
- Genomics
- Question style
- Retrieval
An answer can be uniquely inferred for 54 of 100 questions from submitted scores. Green: correct · Red: incorrect. For questions without a uniquely determined answer: Blue: matches prediction · Orange: differs from prediction. These are inferred answer checks, not official per-question grades.
Galaxy
12/12 terminal item results
UDT = user-defined tool: custom code executed by Galaxy. Route badges summarize analysis tools, excluding uploads and automatic conversions. How usage is counted.
Codex GPT-5.5
3 replicates
Codex GPT-5.5
Replicate 1
Matches predictionNo analysis tools recorded
Answerupstream_gene_variant
- Total tokens
- 622.6K
- Output
- 6.4K
Codex GPT-5.5
Replicate 2
Matches predictionUDT-only
Answerupstream_gene_variant
- Total tokens
- 280.6K
- Output
- 2.0K
Codex GPT-5.5
Replicate 3
Matches predictionUDT-only
Answerupstream_gene_variant
WorkflowEnsembl VEP rsID REST lookup rs2136714166
- Total tokens
- 763.0K
- Output
- 8.2K
Codex GPT-5.6 Sol
3 replicates
Codex GPT-5.6 Sol
Replicate 1
Matches predictionUDT-only
Answerupstream_gene_variant
WorkflowEnsembl VEP API rsID consequence→Verify Ensembl VEP most severe consequence→Extract Ensembl VEP most severe consequence
Codex GPT-5.6 Sol
Replicate 2
Matches predictionUDT-only
Answerupstream_gene_variant
WorkflowEnsembl VEP API rs2136714166
- Total tokens
- 254.3K
- Output
- 2.0K
Codex GPT-5.6 Sol
Replicate 3
Matches predictionUDT-only
Answerupstream_gene_variant
WorkflowEnsembl VEP REST annotation rs2136714166→Ensembl VEP REST annotation rs2136714166 retry
- Total tokens
- 6.0M
- Output
- 12.2K
Codex + DeepSeek-v4-pro-0813
3 replicates
Codex + DeepSeek-v4-pro-0813
Replicate 1
Matches predictionUDT-only
Answerupstream_gene_variant
WorkflowEnsembl VEP rs lookup
- Total tokens
- 344.6K
- Output
- 5.0K
Codex + DeepSeek-v4-pro-0813
Replicate 2
Matches predictionUDT + standard tools
Answerupstream_gene_variant
WorkflowNo Galaxy tool job recorded
- Total tokens
- 4.1M
- Output
- 22.1K
Codex + DeepSeek-v4-pro-0813
Replicate 3
Matches predictionUDT-only
Answerupstream_gene_variant
WorkflowVEP rsID consequence lookup→VEP rsID response diagnostic
- Total tokens
- 541.1K
- Output
- 10.0K
Codex GPT-5.6 Luna
3 replicates
Codex GPT-5.6 Luna
Replicate 1
Matches predictionUDT-only
Answerupstream_gene_variant
WorkflowEnsembl VEP API query for rs2136714166→Ensembl VEP API query for rs2136714166 (retry)→Ensembl VEP API diagnostic for rs2136714166→Ensembl VEP API host diagnostic→Ensembl VEP API assembly check for rs2136714166→1 more tools
- Total tokens
- 1.1M
- Output
- 13.7K
Codex GPT-5.6 Luna
Replicate 2
Matches predictionNo analysis tools recorded
Answerupstream_gene_variant
- Total tokens
- 1.7M
- Output
- 9.7K
Codex GPT-5.6 Luna
Replicate 3
Matches predictionUDT-only
Answerupstream_gene_variant
WorkflowEnsembl VEP rs query→Ensembl VEP rs query consensus→Ensembl VEP rs query with retry
- Total tokens
- 1.6M
- Output
- 10.3K