Back to dashboard

BixBench item

bix-43-q2

Question

What is the odds ratio for p53-mediated cell cycle gene regulation in an enrichment analysis using gseapy with Reactome_2022 using all statistically differentially expressed genes from a pydeseq2 analysis that includes all related treatment groups (DMSO, DMSO_Serum_starvation, Cisplatin_IC50_CBD_IC50, Cisplatin_IC50_CBD_IC50_Serum_starvation_16h) for proper dispersion estimation, after pre-filtering to keep only genes with counts greater than 10 in at least one of all 30 samples, (padj<=0.05, absolute lfc>=0.5, baseMean>=10) between CBD/cisplatin combination treatment and DMSO?

Ideal answer
5.81
Category
RNA-seq,Differential Expression Analysis,Transcriptomics

Galaxy-API code with skills

2/3 pass

replicate 2

pass
Answer5.81798037353593
Workflow
UDT: codex-pydeseq2-gseapy-reactome-or2UDT: codex-pydeseq2-gseapy-reactome-or3UDT: codex-pydeseq2-gseapy-reactome-or4

Galaxy-API code without skills

3/3 pass

Open-ended code with skills

0/3 pass

replicate 1

fail
Answer5.840347891851011
Workflow
local codePyDESeq2GSEApyEnrichrReactome
No Galaxy historyHugging Face trace

replicate 2

fail
Answer6.12816088009491
Workflow
local codePyDESeq2GSEApyEnrichrReactome
No Galaxy historyHugging Face trace

replicate 3

fail
Answer5.84034789185101
Workflow
local codePyDESeq2GSEApyEnrichrReactome
No Galaxy historyHugging Face trace

Open-ended code without skills

0/3 pass

replicate 1

fail
Answer5.840347891851011
Workflow
local codePyDESeq2GSEApyReactome
No Galaxy historyHugging Face trace

replicate 2

fail
Answer5.840347891851011
Workflow
local codePyDESeq2GSEApyReactome
No Galaxy historyHugging Face trace

replicate 3

fail
Answer5.840347891851011
Workflow
local codePyDESeq2GSEApyReactome
No Galaxy historyHugging Face trace