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BixBench item

bix-24-q2

Question

Using differential expression analysis (padj < 0.05, |log2FC| > 0.5) and GO Biological Process enrichment analysis, determine whether upregulation or downregulation of genes primarily drives the metabolic effects of CBD treatment in CRC cells.

Ideal answer
Downregulation
Category
RNA-seq,Differential Expression Analysis,Transcriptomics,Sequence Analysis

Galaxy-API code with skills

3/3 pass

Galaxy-API code without skills

3/3 pass

Open-ended code with skills

3/3 pass

replicate 1

pass
AnswerDownregulation
Workflow
local codePyDESeq2GOg:Profiler
No Galaxy historyHugging Face trace

replicate 2

pass
Answerdownregulation
Workflow
local codeedgeRGOg:Profiler
No Galaxy historyHugging Face trace

replicate 3

pass
Answerdownregulation
Workflow
local codePyDESeq2GO
No Galaxy historyHugging Face trace

Open-ended code without skills

3/3 pass

replicate 1

pass
Answerdownregulation
Workflow
local codePyDESeq2g:Profiler
No Galaxy historyHugging Face trace

replicate 2

pass
Answerdownregulation
Workflow
local codePyDESeq2GOg:Profiler
No Galaxy historyHugging Face trace

replicate 3

pass
Answerdownregulation
Workflow
local codePyDESeq2GOg:Profiler
No Galaxy historyHugging Face trace